The most direct route from Valrico to St. Pete is via I-75 South to I-275 West across the Howard Frankland Bridge, which puts you into downtown St. Pete in roughly 45–55 minutes depending on traffic. The Gandy Bridge is a slightly shorter drive if you're heading to central or south St. Pete and worth taking if I-275 traffic is backed up. Rush hour westbound on Friday afternoons can add 20–30 minutes, so plan accordingly.